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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6cb380740ec20ee85c04b32398d6bc3426991534f1f82b817016b34c823262d' 
  AND token = 'TtnAgINYr5/8IgwD6YK4ScY4173/sW1btC4WCGq2FqI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}