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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd9ecfae14e9828b3037a10905834709a6172da99234e014a724dd9339a2a29b' 
  AND token = 'GuIZHQNlg8/QIVgmc/2HN9ll3kODDsCScjOlkdu9Zg4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}