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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9280d7bc1564ccaf8da8351c7db8c0686b0418c15346ea989bee76ffb7e99fca' 
  AND token = 'saJz3pPZpMxJXkP2Lfck2XFODnlD7tNdmTSYsfbVVR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}