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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d828d0735dd903074250a491770a5c19ba276836f3c0cedd5de602c7199b4cd' 
  AND token = 'mzQJdL3mZwMWbCzK6CTiVQZPxjg3OeB7B1TjF5A3vFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}