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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd421186306d93a01a4bf5c9ea00a1089381616760c5847dc3dab1032747d0c1f' 
  AND token = 'UjE3gHTbR/BLihDQe1USfTp/VLnA1UwvIPKV5Yl1hDA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}