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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0effa229d56759e80044dcfb64d1f4288ade739a11cbdd87e15bab28583c5f0a' 
  AND token = 'yJglAq86U6soTowTavBUid9zveMKylE02CeHSBy4d6Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}