SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d27c157afa664481a09daace5f76fab865bf7f36769009e755d988d51fd7e88' 
  AND token = 'MXcekMzH3qn5DIPJw9cxZMymJXLfGEGhJixQeQNLjx0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}