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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'daa9219b10a666abc5bdd7ab5500f5ee0f09c7f303f42e25e881e72fb0d039fe' 
  AND token = 'b3SPmz4xqxuQlAaK9bRBf8GVNswFYA96ogGxFOt0M6Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}