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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5813992190165f40cc5d1c8045a9a7b84af355814af3ae14bb50df5d7345e8a' 
  AND token = 'eY8ry+t09qmCEZVnhTU0yg/LJQTQdva4pFiTcC90bqA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}