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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27fa96cd86144b812ce9b4e1c7f69766fd07b3d913f609c12e75e5c549fe579c' 
  AND token = 'bXXIvlMMpqagLEcg59MWT5OrEuewpZ7POnznN+NJ1LU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}