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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8db8f725de63351b2f6366cdbb51c469ce5a93c10ddf80e22873344e6a607a20' 
  AND token = '0B4rudfb/CtM7Ar6VCzchQQQBT8JsOnaRk03CJVe3vY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}