SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61e9a45e24d4ada496c39e874c3430a2df81a92389b7cc5f928dc684d21614e7' 
  AND token = '78j/jk5ZgqCFWf0W6txTC4zLAbsQu85y9EdTY7u3wow=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}