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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45501242c54a776b38152e1b1328db464838d13bb5165a8fb3f4aac137606174' 
  AND token = '22M8j0Uxq6raw/NsQNbrdY5fzw6KuzleUFx5551OtKc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}