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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ea4ce845c2b10cfe292d4daedd3aad9a222d0b4638a1cdfe7ce540982bf06da' 
  AND token = 'WZCCQl9na75gFxKQduXShZn8eVTrMgHPy23GEJ0LNTo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}