SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '139ffa2272de0361aa75b1087e97e463b82145e9eeb7866fad0419334ee66737' 
  AND token = 'Q7W5PxJWBDtOT9p1m8A0ivd83Tp8XzQ5VxZPc9PfK5o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}