SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efcb78c0ecd945a0d5674663993933001aa5bb0b3f214ec0364fb627b6ecebdd' 
  AND token = 'ZVbSlaTbYjx7FqPMHVUdYO/AH5AkZkczhN+HPadTPkY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00165

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}