SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0f0ce4e709e83a6a804ad297d22c28e2fb3e4de1405890f50c0806c2aff2363' 
  AND token = 'BRwNJNrb/VqfEDmGDQ9GTCqrYe1wLh9x1W9kzUv5cRE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}