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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1aa6fed7d09a46f981ba5fdc3a46b72b868ec5e30944c09f541dc163795be011' 
  AND token = 'JF4PMtLg751hX79w8hL0qrJY1yLMdOElLR7t0gHF6fM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00065

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}