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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10647abbcd7c5778a3e790f99e6338dc6c7b1f6dabada958ca1209ea996ccc11' 
  AND token = 'OuOp05lEZDMqu7ewWCMUolA/W7cgrGasbwwhYHwwDaU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}