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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95da899b14d227a0e78ffcef7816a9a73d844a99b2c1d3edb8ed5b43d056605d' 
  AND token = 'DE/oycqn7aW8aV83AhVKRhcvJwUcdIdpSg2o50nI3/Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}