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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '219c74a65efe5509cfba003a78f174e805da96a27cfdc21a35e4cd4d2c474c8f' 
  AND token = 'EGfsL6/GnZJ9+qp0Gn5/82ZRT2XtHivVeRtceyNujno=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}