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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc4a8e0186d10984f126131a9b1a879582c1db7b9f90c56321ba8031e6d5597b' 
  AND token = 'Jihf/u97JIpiaYRp5FmQyWsUuzb/mhUkRWNhwcdfX1k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}