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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e640a31e52b8fe1a8644b22d4b4ce28539ccad0250eecc98562fd4ea98ec706f' 
  AND token = 'Mo61kiFQWiUCzjjWNwN2eE0CQL2M6TggUFo41P8iaaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}