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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0578b2548f71ceac1f2e3501c5a5e8e557c2c7276cac837bc04052a4bdf3dec2' 
  AND token = 'uxdqHJiAnpXrA0tCqjKZtCM7m2K3W9NBcmKnfhMw2ro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}