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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00d4eec3994f866a995790936db7e5dc63ed867758a0cd02df25de5370a44f69' 
  AND token = 'Zl2sVmS9NiMqjO+SFOJKzU73XJse2oJueXu+Lw5+qrI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}