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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8b9e4971bd4cee037e4c782e11f44766806ebd007b7b8bc15f497b80748bd9c' 
  AND token = 'tCOs3tdKRxrw0/gTPEECaLsF60+xaesPEYa3TKmlEqY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}