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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26c9e0c226e0c4d46a27b10ee2e8739d006bf62d3b5382422967608b96d1e5ca' 
  AND token = 'xrNPHD2hfFQ1jGZKI3Z3In02h/tduKN8G+v54rbWyMM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}