SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7543ff90ce31ab76fb982efe039147ce02c3ef406158f1f7a3c707a178f29c70' 
  AND token = 'TYFZMdRvCe/1+gfXcSD+L/Zgatv0u6OirsjS9pr2yQU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}