SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '79833c15eb9444ca8718705d4c754945b9da71c296f9de50308428e024608bec' 
  AND token = 'AnViZz4c1XQEwXbbi4E5BFqj4D75CBZ4jq3LGH+SGIY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}