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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c3d3967221e107b1607eaa41a7ea732b02206635f8e6849e833609befe50dee0' 
  AND token = 'YvzW22CsPDYIbDJhi0pYTsuZXVzul8ByCqFWY7AgZZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}