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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acd19c90224f55a278815a4de77f94bad24cdca2ff1282e492f8baa6f5a94136' 
  AND token = '3BpFcEFBBC0G5WO8pTcAfHlqfJLyADhM2KgBFlyWraY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}