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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e178de5f9e871bb9d5d63876c4b9af96106927e8ae467c741ea20517c52a01be' 
  AND token = 'Ilcq2jE8CjOdfdY5P8Cx+X9ND0w9AhLtYk7NxwSRip8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}