SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ed14bbe4e44fc5cc7384ac6a224c12a1d585b04c9b6992aaa2bc443cd9322f8' 
  AND token = '3/D7selucVNEmAm/IhdOoi55hHeFSv4ttYfo7hHc2hI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}