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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57123ffc9f05fa355c6e05396790f364c02778f818f7c3f43e483dda22ec6271' 
  AND token = 'F8SGZX4KshNOwLUcr1tOTRaQ5egsyronV0+MpNp1G1Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}