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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9061ad54348e18207beb1a7bf4bd2f53027ec3b1df062ab78286c05da0107a0f' 
  AND token = 'CMHIOHg9gHeXD2KtvgR9GJ4rR+3+gWxrlTUQz1zp5vs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}