SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1324953eb92e3077c4b4e70226becd68f4621fb02c777daa44065ab9a4dc0d4d' 
  AND token = '0SiTv6XbOR2repNgAPZ/lihDD+FipHNJBZ9eXFi0VTU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}