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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a6001286d3af13d9c2a6140cb94e3eaba1f8482a9c3467a275cd6e2b7e8082a' 
  AND token = 'bKmw00C6LL0wDUlfkfuM3enPCXhCGrjV+0BuzgB+zeU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}