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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c0e22a2f73e6ca9427f905542413896861d6ab7d022733ae62a37ae86ed60fc' 
  AND token = 'm5Ie9bDFSurmJPsI6Rh0rX9KgbrfhXGmuOqcYP3FgL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}