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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d4486ce9c63f9cd17569076954c7e19a70b64d4b4d50e68944f59af63dbeeda' 
  AND token = 'H3eJ0a+vtEjpzhAxIE1Q6/n2i7m+9WNs4pJMViN27YE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}