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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2c643047fc227d3a7f713e310f58edff50b0eff3cbacc70bed42b8715f6575d' 
  AND token = '+6Tl0Lio0ypeo+eURQFDI1fDaz+2j+rlRSuBwhZgGm8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}