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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ef3abd29031f67e8a2b54cadb67377d952e6f4f24811fe0cf429badef7b8f9a' 
  AND token = 'GePjK87rimDHpkryks9c18VyeCUTK4+fPqIcm2rRtBc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}