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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45acdd10338cfd2e936c84d5f2747306711a91c2480b6ac2efc673005f958286' 
  AND token = '6UcCmU6I0agZSAgLpBNy3VtEwIQYzHn5FyBz7HIKc94=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}