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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fba35289d686d1b5485d57f6e5b166f6df67bc5ed0ca30c87188337333f2f01' 
  AND token = 'tP3qdAzxyHLp/FFDR4sTE20qX6yAJb/gmhyXlgoSabE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}