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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4503022b22bec39d4d87981ac6c1a202502fb8a50a2e8602195d0e90040a592e' 
  AND token = 'KR8FLQ2LJbiutsche/5brbK+rixfTvxaQlNPG/th7Us=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}