SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c546973c1990f439268ee88ab9cb5d752ab31b89e3c30ac569da8a4d20bfc273' 
  AND token = 'IXqgcASLoUAIC95No1/CxRrZGHgalZoiXuVXR/FEk5s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}