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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e14fa9eb82cab3f20f50b292d591648d6fb4e07861278c5aa76887b2d4add8a' 
  AND token = 'nIeJc7ibSxga9FhSsKFhd3uAMRwRO/f4kSe0UhvP3bA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}