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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8f482ef8771d42673197f4338305cb64059da9e6b6acffef13726546561ed46' 
  AND token = '0Bdjs8EwMFaY7TsN3ql1egc7PEuN77rsP0bCw5SRsm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}