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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e8116b7c8469e0cb5bff97735bea4c975a53616a6dda9e5441575be07399b30' 
  AND token = '5LiBCZ5Ai25/wE4/RhfyxAFfaTXEfe9o3e10Nw6gdTU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}