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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4708667733de36751ab7251965ae94d05d14ef6294bac3a6bbd75a495e1cbef' 
  AND token = 'hr6Y2YUQgl6wfT4/cMLTtIVAVsyGIqcQnSQVahqCwmY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}