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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '361c00f8b7594d1c31c471a4d64c5587511b22364149db9bbbd520cfadc6c028' 
  AND token = 'MqGDFewRxdzyWEswIvO61rXZDRtvviJurwmHJf2jAy0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}